Cerebral Spinal Fluid


Cerebral Spinal Fluid, CSF

  • Definitions
  1. Cerebrospinal Fluid
    1. Clear, colorless fluid produced in the Choroid plexus within the walls of the Cerebral Ventricles
    2. Flows through the Cerebral Ventricles within the subarachnoid space
    3. Surrounds and protects the brain and spinal cord
  • Physiology
  1. Choroid Plexus: Formation of CSF
    1. Tufts of capillaries in Lateral Ventricles
    2. Produces CSF at 20 ml/hour (up to 500 ml/day)
  2. Pathway
    1. See Cerebral Ventricle for Cerebrospinal Flow
    2. CSF flows down Magendie and Luschka canals and via subarachnoid space around the brain and spinal cord
  3. CSF Reabsorption
    1. CSF reabsorption at the arachnoid villi and dural sinuses
    2. Drains into the internal Jugular Veins
  4. CSF Volume
    1. Total CSF in circulation: 140 ml
    2. Distribution
      1. Ventricles: 25 ml
      2. Subarachnoid space: 115 ml
  • References
  1. Gilman (1989) Manter and Gatz Essentials of Neuroanatomy and Neurophysiology, Davis, p. 232-7
  2. Goldberg (2014) Clinical Neuroanatomy, p. 6-15