Surgery

Hepatomegaly in Newborns

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Hepatomegaly in Newborns, Splenomegaly in Newborns, Neonatal Hepatomegaly, Liver Mass in Infants, Congenital Liver Mass

  1. Splenomegaly
    1. TORCH Virus Infection
    2. Bacterial Infection (e.g. Spirochetes) or Sepsis
    3. Disordered carbohydrate metabolism
      1. Galactosemia
      2. Hereditary Fructose Intolerance
  2. No Splenomegaly
    1. Causes found on right upper quadrant Ultrasound
      1. Hepatoma or Hemangioma and other tumor
      2. Choledochal cyst
    2. Causes found on biliary scan
      1. Biliary atresia
    3. Causes found on liver biopsy
      1. Neonatal hepatitis
      2. Toxin exposure
      3. Parenteral nutrition
  1. Studies
    1. Abdominal Ultrasound
  2. Causes with Splenomegaly
    1. Vascular obstruction
    2. Liver tumor (e.g. Hepatoblastoma)
    3. Metabolic disease
  3. Causes without Splenomegaly
    1. Tumor
    2. Mother with Gestational Diabetes
    3. Malnutrition
  • References
  1. Cloherty (1991) Neonatal Care, p. 449
  2. Wolf (2000) Pediatr Rev 21(9):303-10 [PubMed]