NICU

Neonatal Chlamydia Pneumonia

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Neonatal Chlamydia Pneumonia

  • Epidemiology
  1. Incidence: 12,000 cases per year in United States
  2. Occurs in <10% of vaginal deliveries from mothers with active genitourinary Chlamydia
  • Pathophysiology
  1. Chlamydia trachomatis infection in the newborn acquired via vertical transmission during delivery from a mother with chlamydia Vaginitis
  2. Not the same as the Atypical Pneumonia of Chlamydia pneumoniae (TWAR) seen in the elderly and to a lesser extent in young adults
  • Symptoms
  • Onset 1-3 months after delivery
  1. Tachypnea
  2. Staccato Cough (coughing in short bursts)
  3. No fever
  1. Hyperinflation
  2. Bilateral diffuse infiltrates
  • Labs
  • Management
  1. Erythromycin base or EES 50 mg/kg divided four times daily for 14 days
  2. Second course may be required
  3. Close interval follow-up