Lab

Obstructive Lung Disease

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Obstructive Lung Disease, Obstructive Lung Function

  • See Also
  1. Pulmonary Function Test
  2. Lung Volumes
  3. Diffusing Capacity
  4. Inhalation Challenge Test
  5. Exercise Spirometry
  6. Functional Residual Capacity
  7. Vital Capacity
  8. Peak Expiratory Flow Rate (PEFR)
  9. Spirometry Lower Limit of Normal (PFT LLN)
  10. Restrictive Lung Disease
  • Causes
  1. Alpha-1-Antitrypsin Deficiency
  2. Asthma
  3. Bronchiectasis
  4. Bronchiolitis Obliterans
  5. Chronic Obstructive Pulmonary Disease
  6. Cystic Fibrosis
  7. Silicosis (early stages)
  1. Criteria
    1. FEV1 to FVC Ratio <0.7 (or <LLN or for children<85% of predicted) AND
    2. Normal FVC or FVC response to Bronchodilator
  2. Approach
    1. Assess Severity
      1. See FEV1 interpretation above
    2. Assess Bronchodilator response
      1. Bronchodilator response with FEV1 or FVC increased >12% at any age (or >200 ml in adults)
        1. Consistent with reversible Obstructive Lung Disease (Asthma)
      2. Inadequate Bronchodilator response
        1. Consistent with irreversible Obstructive Lung Disease (COPD)
  • References
  1. Johnson (2014) Am Fam Physician 89(5): 359-66 [PubMed]