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Allergic Bronchopulmonary Aspergillosis

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Allergic Bronchopulmonary Aspergillosis, ABPA

  • Background
  1. Aspergillus fumigatus colonization of airways and mucus
  • Risk Factors
  • Components
  1. Bronchial Asthma
    1. Due to IgE mediated hypersensitivity
  2. Bronchiectasis
    1. Due to immune complex deposition in proximal airways
  • Diagnosis
  • Labs
  1. Peripheral Eosinophilia
  2. Serum precipitans to a. fumigatus
  3. Serum IgE increased
  1. Immediate wheal and flare reaction to a. fumigatus
  • Management
  1. Long-term use of Systemic Corticosteroids