COPD
Emphysema
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Emphysema
See Also
COPD
Chronic Bronchitis
COPD Management
Acute Exacerbation of Chronic Bronchitis
Antibiotic Use in COPD Exacerbation
COPD Exacerbation Prevention
COPD Action Plan
Definition
Chronic Obstructive Pulmonary Disease
"
Lung
Dry Rot"
Alveolar distention
Destruction of alveolar septae
Type
Panacinar
Affects both central and peripheral portions acinus
Centriacinar
Affects primarily
Bronchi
oles and alveolar ducts
Minimal involvement of peripheral acini
Symptoms
Scant
Sputum
production
Exertional
Dyspnea
Signs
"Pink Puffer"
Thin, dyspneic patient with mild
Hypoxia
Contrast with "Blue Bloater" of
Chronic Bronchitis
Tachypnea
Prolonged expiration
Hyperresonant chest
Diminished breath sounds
Labs
Arterial Blood Gas
(ABG)
Slightly decreased arterial pO2
Slightly decreased arterial pCO2
Pulmonary Function Test
s
FEV1 reduced
Diffusion capacity (
DLCO
) reduced
Staging
See
COPD Staging
Imaging
Chest XRay
Hyperinflated lungs
Management
SEE
COPD Management
Lung
reduction surgery
Removal of most severely damaged lung (n=20)
Increased mean lung elastic recoil by 27%
Increased FEV1
Increased FVC
Reduced FRC and RV
Improved walking capacity
References
Sciurba (1996) N Engl J Med, 334:1095-9 [PubMed]
Complications
Cor Pulmonale
Hypercapnic
Respiratory Failure
References
Wilson (1991) Harrison IM, McGraw-Hill, p.1074-82
Martinez (1998) Postgrad Med 103(4):112-25 [PubMed]
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