Asthma

Intrinsic Asthma

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Intrinsic Asthma, Non-allergic asthma, Non-Type 2 Asthma, Non-T2 Asthma

  • Epidemiology
  1. Much more common in adults than children
  2. Onset age over 40 years old
  • Pathophysiology
  1. Non-IgE, Non-allergic asthma
  2. Neutrophil mediated Asthma
  • Causes
  • Precipitating Factors
  1. Irritant exposure
    1. Air Pollution
    2. Fumes
    3. Perfumes
    4. Household cleaning agents
    5. Insecticides
    6. Fresh paint
    7. Tobacco Smoking or Secondhand Smoke
    8. Cold air
  2. Infection
    1. Upper Respiratory Infection
    2. Purulent Rhinitis
    3. Acute Sinusitis
  3. Gastroesophageal Reflux
  4. Medications
    1. Beta Blockers (even Intraocular Beta Blocker)
  5. Body Habitus
    1. Obesity
  • Symptoms