STD

Mycoplasma Genitalium

search

Mycoplasma Genitalium

  • Pathophysiology
  • Labs
  1. Screening Indications
    1. Symptomatic patients with Urethritis or Cervicitis
    2. Pelvic Inflammatory Disease (consider)
    3. Persistent Epididymitis
    4. Avoid testing in isolated Vaginal Discharge
  2. Mycoplasma Genitalium PCR (NAAT)
    1. Obtain sample from first void urine sample, vulvovaginal swab or rectal swab
    2. Reflex Macrolide resistance testing is available from some labs
  • Management
  1. Macrolide Resistance (or unknown, testing unavailable)
    1. First: Doxycycline 100 mg orally twice daily for 7 days
    2. Next: Moxifloxacin (Avelox) 400 mg orally daily for 7 days
  2. Macrolide Sensitive
    1. First: Doxycycline 100 mg orally twice daily for 7 days
    2. Next: Azithromycin 1000 mg on Day 1, then 500 mg daily on days 2, 3 and 4