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Fourth Generation Fluoroquinolone

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Fourth Generation Fluoroquinolone, Fourth Generation Quinolone, Trovafloxacin, Trovan

  • See Also
  1. Fluoroquinolone
  • Preparations
  1. Trovafloxacin (Trovan)
  • Pharmacology
  • Activity Spectrum
  1. Gram Negative Bacteria (Enterobacteriaceae)
  2. Atypical Bacteria
  3. Staphylococcus aureus (Methicillin susceptible)
  4. Streptococci
    1. Improved coverage over Third Generation Quinolones
  5. Anaerobic Bacteria
    1. Not covered by Third Generation Quinolones
  6. Minimal Pseudomonas aeruginosa coverage
  • Indications
  1. Intra-abdominal infections
  2. Avoid in UTI (low urine concentrations)
  • References
  1. King (2000) Am Fam Physician 61(9):2741-8 [PubMed]
  2. O'Donnell (2000) Infect Dis Clin North Am 14(2):489-513 [PubMed]
  3. Oliphant (2002) Am Fam Physician 65(3):455-64 [PubMed]
  4. Owens (2000) Med Clin North Am 84(6):1447-69 [PubMed]