Lab

Immunoglobulin G

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Immunoglobulin G, IgG Immunoglobulin, Gamma Globulin G, IgG

  • Normal
  1. Range: 800-1500 mg/dl
  2. Varies by age
  • Physiology
  1. Crosses maternal-fetal membrane
  2. Interacts with complement system
  3. Enhances phagocytosis by binding Macrophages and PMNs
  4. Enhance cytotoxicity by binding Natural Killer Cells
  • Decreased
  1. Hypo-IgG
  2. Protein losing Enteropathy
  3. Nephrotic Syndrome
  • Increased
  1. Chronic granulomatous infection
  2. Inflammation
  3. Multiple Myeloma
  4. Liver disease
  5. Infections
  6. Autoimmune Disease