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Twinrix

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Twinrix, Combined Hepatitis A and Hepatitis B Vaccine

  • Preparation
  • Components of Twinrix Vaccine
  1. Killed Hepatitis A Virus and
  2. Recombinant Hepatitis B
  • Dosing
  1. Adults: 720 EU/20 ug (1.0 ml)
  2. Standard 3 dose series (same schedule as Hepatitis B Vaccine schedule)
    1. Dose 1: Month 0
    2. Dose 2: Month 1
    3. Dose 3: Month 6
  3. Alternative accelerated 4 dose series
    1. Dose 1: Day 0
    2. Dose 2: Day 7
    3. Dose 3: Day 21-30
    4. Dose 3: Month 12
  • Contraindications
  1. Not approved for use in Children (age <18 years)
  • Resources
  1. CDC Immunization Schedules (last accessed 10/28/2020)
    1. https://www.cdc.gov/vaccines/schedules/