Pharm
Hematopoietic Stem Cell Transplant
search
Hematopoietic Stem Cell Transplant
, Stem Cell Transplant, HSCT, Stem Cell Transfusion
Indication
Leukemia
management
Bone Marrow
Suppression following high dose chemo
Advantages
Compared with
Bone Marrow Transplant
More effective than
Bone Marrow Transplant
Much easier to harvest
Identify CD34
Antigen
via
Monoclonal Antibody
Small volume of peripheral stem cells effective
Greater disease free survival than
Bone Marrow
Shorter hospitalization (2 weeks rather than 3 weeks)
Much less costly
Management
Surveillance of survivors treated with Hematopoietic Stem Cell Transplantation
Complete Blood Count
with differential
Every 1-2 months for 3 years THEN
Every 3-6 months for up to 5 years THEN
Annually
Testing at one year following Stem Cell Transplantation
CD4 Cell Count
Immunoglobulin
level
Bone density
Ophthalmic exam
Annual lab testing
Comprehensive metabolic panel
Includes serum
Electrolyte
s,
Serum Glucose
,
Serum Creatinine
,
Blood Urea Nitrogen
and
Liver Function Test
s
Thyroid Stimulating Hormone
Urinalysis
and
Urine Microalbumin
Serum Ferritin
Vitamin D
Hemoglobin A1C
Serum Testosterone
in males
Follicle Stimulating Hormone
(FSH) and
Luteinizing Hormone
(LH) in females
Routine
Health Maintenance
Dental exams at least annually
Routine cancer screening
Immunization
s
Pulmonary Function Test
indications
If abnormal prior to treatment
References
(1995) Med Lett Drugs Ther 37(955): 71 [PubMed]
Rizzo (2006) Biol Blood Marrow Transplant 12(2): 138-51 [PubMed]
Type your search phrase here