Exam
Plasmic Score
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Plasmic Score
, ADAMTS13 Enzyme Activity Prediction Tool
Indications
Suspected
Thrombotic Thrombocytopenic Purpura
(TTP)
Mechanism
Low ADAMTS13 Enzyme Activity <10% is associated with TTP
Criteria
Assign one point for each positive criteria
Platelet Count
<30,000/uL
Hemolysis
No cancer history
No organ
Transplantation
history
Mean Corpuscular Volume
(MCV) <90
Serum Creatinine
<2 mg/dl (<177 uMol/L)
INR <1.5
Interpretation
Plasmic Score based on total points from criteria above
Score 0 to 4
Low risk (4.3%) of Low ADAMTS13 Enzyme Activity
Score 5 to 6
Intermediate risk (56.8%) of Low ADAMTS13 Enzyme Activity
Score >6
High risk (96%) of Low ADAMTS13 Enzyme Activity
References
Bendapudi (2014) Blood 124(21): 231 [PubMed]
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