Pharm

Nevirapine

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Nevirapine, Viramune, NVP

  • Efficacy
  1. Good benefit in combination with 2 nucleosides
  • Dosing
  1. Start: 200 mg PO qd for 14 days
  2. If no rash, increase dose to 200 mg PO bid
  • Adverse effects
  1. See NNRTI for class related adverse effects
  2. Severe hepatoxicity and liver failure risk if pre-treatment CD4 >250 in men or >400 in women