Pharm

Fusion Inhibitor

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Fusion Inhibitor, Enfuvirtide, Fuzeon

  • Class
  1. Anti-retroviral agent
  2. Fusion Inhibitor
  • Indications
  1. Treatment-experienced patients
  2. Limited use in clinical practice
  • Mechanism
  1. Blocks HIV to chemokine receptor binding on CD4 cells
  • Adverse Effects
  1. Injection site pain and reaction (common)
  2. Eosinophilic Hypersensitivity Reaction (<1%)
  3. Neutropenia
  4. Increased risk of Bacterial Pneumonia