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BRCA2

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BRCA2

  • Location
  1. Chromosome 13
  • Epidemiology
  1. Defective gene connotes:
    1. Breast Cancer risk: 90%
    2. Ovarian Cancer risk: 15-20% (less than BRCA1)
  2. Responsible for a third of hereditary Breast Cancer
  3. Affects Male as well as Female members
  • References
  1. (1994) Science 265:2088 [PubMed]
  2. (1995) Lancet 346:544 [PubMed]