Pharm

Intraocular Alpha-2 Adrenergic Agonist

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Intraocular Alpha-2 Adrenergic Agonist, Intraocular Alpha-Adrenergic, Apraclonidine, Lopidine, Brimonidine, Alphagan, Lumify, Mirvaso

  • Preparations
  1. Apraclonidine (Lopidine)
  2. Brimonidine (Alphagan)
    1. Available as combination with Brinzolamide (Simbrinza)
    2. Mirvaso (Brimonidine gel)
      1. Indicated for Eye Redness due to Rosacea
    3. Lumify (OTC Brimonidine 0.025%) released in 2018
      1. Marketed as OTC to reduce Eye Redness
      2. No proof that it is more effective than OTC ocular Decongestants (e.g. visine) and more expensive
      3. Evaluate Eye Redness for underlying cause instead
      4. (2018) presc lett 25(6): 35 [PubMed]
  • Mechanism
  1. Decrease Aqueous Humor production
  • Drug Interactions
  • Adverse Effects
  1. Eye itching
  • Efficacy