Pharm
Human Growth Hormone
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Human Growth Hormone
, Growth Hormone, hGH
Indications
Medical Uses
Used to enhance growth in
Short Stature
Illicit uses
Ergogenic Aid
used by athletes
Similar effect as with
Anabolic Steroid
s
Difficult to detect
Expensive (>$1000/month)
Mechanism
Liver
converts GH to
Insulin
-like growth factor (IGF-1)
Precursor to testosterone
Source
Initially derived from cadavers in 1950's
Transmitted
Creutzfeldt-Jakob Disease
to patients
Now produced by recombinant
Genetics
Gene
ntech developed
Soma
trem (Protropin) in 1990s
Dosing
Available only via injection
Adverse Effects
Growth-hormone induced
Myopathy
Muscles hypertrophy, but are weaker than before
Acromegaly
Diabetes Mellitus
Cardiomyopathy
Congestive Heart Failure
May be related to
Leukemia
development
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