Lab

Serum Cortisol

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Serum Cortisol, Serum Cortisol Measurement

  • Interpretation
  • Normal
  1. Cortisol 8 am: 4-19 mcg/dl
    1. Consider dynamic testing if early morning testing<13 mcg/dl
  2. Cortisol 4 pm: 2-15 mcg/dl
  • Interpretation
  • Increased
  1. Cushing's Disease
  2. Ectopic ACTH production
    1. Small-cell Lung Cancer
  3. Chronic Renal Failure
  4. Pregnancy
  • Interpretation
  • Decreased
  1. Primary or Secondary adrenocortical insufficiency
  2. Anterior pituitary dysfunction