Pharm
Palforzia
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Palforzia
, Peanut Allergen Powder
See Also
Food Allergy
Immunotherapy
Indications
Peanut Allergy
Desensitization
in ages 4 to 17 years old
Goal to reduce severity of reactions (NOT to reintroduce peanuts into diet)
Alternative to peanut oral
Immunotherapy
(performed by allergists)
Efficacy
Following 1 year of
Desensitization
, two thirds of children are expected to tolerate 2 peanuts without reaction
Precautions
Peanut free diet must be followed regardless of
Desensitization
Keep
Epinephrine Autoinjector
nearby (reactions will be more common during
Desensitization
)
Disadvantages
Cost: $890 per month
Must be in office to start medication and at each titration up in dose
Restart in clinic if >3 doses missed
Dosing
Risk Evaluation and Mitigation Strategy (
REMS
) required for prescribers
Taken daily and gradually increasing doses
References
(2020) Presc Lett 27(10): 58
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