Pharm
C1 Human Esterase Inhibitor
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C1 Human Esterase Inhibitor
, C1 Antagonist, C1 Inhibitor, Berinert
See Also
Angioedema
Bradykinin Receptor Antagonist
Indications
Severe, airway compromising
Angioedema
Hereditary Angioedema
(treatment of choice)
ACE Inhibitor
Angioedema
(may be effective)
Dose
Berinert 20 IU/kg IV for 1 dose
Cost: $3000 per dose
Adverse Effects
Headache
(common)
Nausea
(common)
Dizziness
Fever
Local skin reaction and Rash
Flu-like symptoms
Hypersensitivity Reaction
(uncommon)
Thrombotic event, especially at doses higher than recommended (uncommon)
References
(2015) Lexicomp, accessed online 4/9/2015
Farkas (2007) J Allergy Clin Immunol 120(4):941-7 +PMID:17761272 [PubMed]
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