Pigment

Hyperpigmentation

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Hyperpigmentation

  • Causes
  • Systemic conditions with Hyperpigmentation
  1. Skin
    1. Scleroderma
  2. Endocrine and Metabolic
    1. See Hyperpigmentation in Pregnancy
    2. Grave's Disease
    3. Hyperthyroidism
    4. Addison's Disease (Melanin Deposition)
    5. Porphyria
    6. Diabetic Dermopathy
      1. Hemosiderin deposition in Diabetes Mellitus
  3. Gastrointestinal Disease
    1. Whipple's Disease
    2. Cirrhosis
    3. Felty's Syndrome
    4. Hemochromatosis (Iron deposition)
  4. Genitalia
    1. Heller-Nelson Syndrome
  5. Hematology and Oncology
    1. Pernicious Anemia
    2. Folic Acid Deficiency
    3. Neoplasm
  6. Nutrition
    1. Malnutrition
    2. Starvation
  7. Medications and toxins
    1. See Medication Causes of Hyperpigmentation
    2. Phototoxic Reaction (increased Melanocytes)