Pharm

Cantharidin

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Cantharidin

  • Mechanism
  1. Vesicant obtained from Blister beetle
  • Indications
  1. Stubborn periungual warts
  2. May be useful in Molluscum Contagiosum in children
  • Obtaining
  1. No longer available is U.S., but available in Canada
  2. Manufactured by Omniderm
    1. Phone: 1-888-458-0158
    2. Fax: 1-514-458-1477
  • Preparations
  1. Cantharidin (Cantharone, Canthacur)
  2. Canthacur PS (w/ Podophyllin 5% + Salicylic Acid 30%)
    1. Reserve for Plantar Warts due to irritation
  • Precautions
  1. Apply ONLY in office
  2. Avoid touching normal skin
  • Application
  1. Allow liquid to dry over wart
  2. Then cover with occlusive tape (e.g. Blenderm)
  3. Remove tape after 24 hours
    1. Remove earlier for significant discomfort
  4. In 2-3 days remove Blister under Local Anesthesia
    1. Snip off near base OR Curette
    2. Benefits of removing Blister
      1. Prevents progression to ring wart
      2. Prevents recurrence
  • Follow-up
  1. Consider repeat treatment weekly as tolerated