Acne Neonatorum


Acne Neonatorum, Neonatal Acne, Acne in the Newborn

  • Epidemiology
  1. Onset in up to 20% of newborns
  • Pathophysiology
  1. Maternal androgenic Hormones stimulate Sebaceous Glands
  2. Resolves without scarring when maternal Hormones wane after 3-4 months
  • Signs
  1. Distribution: Face
    1. T-Zone: Forehead, nose and chin
  2. Characteristics
    1. Comedones (typically closed comedones)
    2. Inflammatory Papules, Pustules and Nodules may occur
  • Differential Diagnosis
  1. Neonatal Pustules and Vessicles
  2. Hyperandrogenism (e.g. adrenal cortical hyperplasia)
    1. Consider in severe, refractory and persistent cases
  • Management
  1. Resolves spontaneously without treatment
  2. Treatment can be used if parents wish
    1. Over the counter acne soaps (low pH)
    2. Sparing use of Benzoyl Peroxide lotion 2.5% (test first on antecubital fossa)
  • References