Pharm

Potassium-Sparing Diuretic

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Potassium-Sparing Diuretic, Amiloride, Midamor, Triamterene, Dyrenium

  • Preparations
  1. Potassium-Sparing Diuretics only
    1. Amiloride (Midamor)
    2. Triamterene (Dyrenium)
  2. Potassium-Sparing Diuretic and Aldosterone Antagonists
    1. Spironolactone (Aldactone)
    2. Eplerenone (Inspra)
  • Precautions
  1. Monitor Serum Potassium after starting a Potassium-Sparing Diuretic in those at Hyperkalemia risk
    1. Obtain Serum Potassium at 3 days, 7 days and then monthly for the first 3 months
  • Drug Interactions
  1. Potassium supplements (risk of Hyperkalemia)
  2. CYP3A4 Inhibitors (Eplerenone only)
    1. Significantly increases Eplerenone levels