Pharm

Nifedipine

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Nifedipine, Procardia, Adalat, Afeditab

  • Precautions
  1. Write for generic Nifedipine ER to allow pharmacist to substitute between multiple similar ER preparations
    1. (2016) Presc Lett 23(7): 39-40
  • Contraindications
  1. Congestive Heart Failure
  2. Aortic Stenosis
  3. Avoid in Diabetes Mellitus (may increase Proteinuria)
  4. Concomitant use of Magnesium Sulfate
    1. Theoretically deactivates Calcium Gluconate antidote
  1. Nifedipine (Procardia) XL 30-60 mg PO qd (Maximum 120 qd)
  1. Load: Nifedipine 10 mg sublingual every 20 minutes for 3 doses
  2. Maintenance: Nifedipine10 to 20 mg PO every 4 to 8 hours
  • Adverse Effects
  1. Please see Calcium Channel Blockers
  2. Avoid short acting agents (increased coronary risk)
  3. Fetal effects
    1. Risk of Intrauterine Growth Retardation