Pharm
Esmolol
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Esmolol
, Esmolol Hydrochloride, Brevibloc
See Also
Beta Blocker
Mechanism
Selective
Beta Blocker
Indications
Atrial Fibrillation Rate Control
Emergent
Hypertension Management
Pharmacokinetics
Half-life: 9 minutes
Duration of action: 15-20 minutes
Dosing
Intravenous
Preparation: 2.5g (10 ml ampule) in 250 ml (10 mg/ml)
Load: 250-500 ug/kg over 1 min (70 kg: 35 mg, 3.5 ml)
Infusion:
Start 25-50 ug/kg/min IV (70 kg: 10 ml/h)
Titrate up 25-50 ug/kg q5 min to max 300 ug/kg/min
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