Pharm
Beta Blocker Overdose
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Beta Blocker Overdose
, Beta Blocker Toxicity
See Also
Beta Blocker
Calcium Channel Blocker Overdose
Drug
Overdose
Pathophysiology
Selective
Beta Blocker
s lose selectivity in
Overdose
Overdose
d
Beta Blocker
s affect all receptors regardless of whether agent is beta-1 or beta-2 selective
Beta Blocker Overdose is treated the same as
Calcium Channel Blocker Overdose
Precautions
Beta Blocker Overdoses are high risk of death (on par with
Tricyclic Antidepressant
s and
Calcium Channel Blocker
s)
Treat at similar intensity as a full code as these patients decompensate rapidly
Symptoms and Signs
Primary toxic effects
Bradycardia
Hypotension
Other effects
Acidosis
Bronchospasm
Coma
Hypoglycemia
(esp. in children)
Contrast with
Hyperglycemia
in
Calcium Channel Blocker Overdose
Hyperkalemia
Respiratory depression
Lipophilic
Beta Blocker
s (primarily
Propranolol
, but also
Metoprolol
and Pindolol)
Seizure
s
QRS Widening
Management
See
Calcium Channel Blocker Overdose
for management
Specific concerns with Beta Blocker Overdose (contrast with calcium channel
Overdose
)
Hypoglycemia
Monitor
Glucose
every 30 min (more often if on euglycemic
Insulin
protocol)
Start D10 if
Glucose
is trending downward
References
Yen (2015) Crit Dec Emerg Med 29(10): 18-23
Anderson (2008) Clin Pediatr Emerg Med 9(1): 4-16 [PubMed]
Kerns (2007) Emerg Med Clin North Am 25(2):309-31 [PubMed]
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