Urology Book


Urine Ketone

Aka: Urine Ketone, Urine Ketone Test Strip
  1. See Also
    1. Urinalysis
    2. Serum Ketone
    3. Ketone
  2. Mechanism
    1. Urine Dipstick detects acetic acid (Acetoacetate)
      1. In Diabetic Ketoacidosis, Beta-Hydroxybutyrate (primary Ketone) is converted to Acetoacetate
    2. Confirmatory Test
      1. Urine
        1. Acetest tablet test
      2. Serum Ketone (preferred)
        1. Beta-Hydroxybutyrate
          1. Preferred Serum Ketone test
        2. Basic chemistry panel
          1. Ketoacidosis
            1. Low serum bicarbonate
            2. Increased Anion Gap
          2. Normal or resolving Ketoacidosis
            1. Normal serum bicarbonate
            2. Normal Anion Gap
  3. Interpretation: Normal
    1. Negative
  4. Causes: True Positive Urine Ketones
    1. Dehydration
    2. Starvation or Low Carbohydrate Diets (Ketogenic Diet)
    3. Diabetic Ketoacidosis (DKA)
    4. Alcoholic Ketoacidosis
    5. Isopropanol toxicity
    6. Pregnancy
  5. Causes: False Positive Urine Ketones
    1. Low Urine pH (acidic)
    2. Increased Urine Specific Gravity
    3. Phenolphthalein
    4. Levodopa
  6. Causes: False Negative Urine Ketones
    1. Delayed Urine Exam
    2. Not all Ketones (Beta-Hydroxybutyrate, Acetoacetate, Acetone) are detected by all Urine Dipstick tests
      1. Most Urine Dipsticks detect Acetoacetate
  7. References
    1. Hitzeman (2022) Am Fam Physician 106(1): 27-35 [PubMed]
    2. Simerville (2005) Am Fam Physician 71(6): 1153-62 [PubMed]

Urine ketone test (C0555179)

Concepts Laboratory Procedure (T059)
SnomedCT 144521000, 167294004, 144530008, 167285005
English Urine ketone test NOS, acetonuria (lab test), urine ketones (lab test), urine ketones, urine tests nonspecific abnormal findings acetonuria, acetonuria, Urine ketone test, ketones, ketone tests urine, urine ketones test, ketones urine test, urine ketone test, Urine ketone test NOS (procedure), Urine Ketones Test, Urine ketone test (procedure)
Spanish prueba de cetonuria, SAI, prueba de cetonuria, SAI (procedimiento), Urine ketone test NOS, prueba de cetonuria (procedimiento), prueba de cetonuria
Derived from the NIH UMLS (Unified Medical Language System)

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