Urology Book


Split 24 Hour Urine Protein

Aka: Split 24 Hour Urine Protein
  1. Indication
    1. Suspected Orthostatic Proteinuria
  2. Technique
    1. See 24 hour Urine Collection
    2. Start collection after first morning void (e.g. 7 am)
    3. Bottle 1
      1. Collect daytime urine sample over first 16 hours
      2. Void immediately before bedtime
    4. Bottle 2
      1. Collect 8 hour overnight (supine) specimen
      2. Include first morning void in collection
  3. Interpretation
    1. Glomerular disease: Bottle 2 with >50 mg Protein
    2. Orthostatic Proteinuria: Bottle 2 with <50 mg Protein

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