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Pentobarbital
Aka: Pentobarbital- See Also
- Mechanism
- Dose
- Dose: 2.5 mg/kg IV (may repeat additional 1.25 mg/kg as needed twice)
- Observe for Hypotension
- Indications: Brief Procedural Sedation
- Rare use in U.S. now
- Ideal for CT Head (brief action, Seizure Prophylaxis)
- May be accompanied to CT with RN (low risk of respiratory depression, or other serious adverse effects)
- Adverse Effects
Pentobarbital (C0030883) |
|
|---|---|
| Definition (MSH) | A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236) |
| Definition (CSP) | short to intermediate acting barbiturate used as a sedative and hypnotic; the sodium salt is also used as an anticonvulsant, as a preanesthetic and as an adjunct to anesthesia. |
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | D010424 |
| SnomedCT | 360214003, 33231001, 372703009 |
| LNC | LP16241-9, MTHU003433 |
| English | Mebubarbital, Pentobarbital, Pentobarbitone, 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylbutyl)-, Pentobarbital [Chemical/Ingredient], pentobarbitone, PENTobarbital, pentobarbital (discontinued), pentobarbital (medication), Pentobarbitone - chemical (substance), Pentobarbitone - chemical, pentobarbital, Pentobarbital (product), Pentobarbital (substance), PENTOBARBITAL |
| Swedish | Pentobarbital |
| Czech | pentobarbital |
| Finnish | Pentobarbitaali |
| Russian | NEMBUTAL, ETAMINAL, PENTOBARBITAL, MEBUMAL, NEBUMAL, MEBUBARBITAL, МЕБУБАРБИТАЛ, НЕБУМАЛ, НЕМБУТАЛ, ПЕНТОБАРБИТАЛ, ЭТАМИНАЛ, МЕБУМАЛ |
| Japanese | ペントバルビタール, メブマール, メブバルビタール |
| Italian | Pentobarbitone, Pentobarbital |
| Spanish | pentobarbitona - compuesto químico, pentobarbital - compuesto químico (sustancia), pentobarbital - compuesto químico, pentobarbital (producto), pentobarbital (sustancia), pentobarbital, pentobarbitona - compuesto químico (sustancia), pentobarbitona, Mebubarbital, Pentobarbital |
| Polish | Nembutal, Pentobarbital |
| French | Pentobarbital |
| German | Mebubarbital, Pentobarbital |
| Portuguese | Mebubarbital, Pentobarbital |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
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