Surgery Book


Murphy Sign

Aka: Murphy Sign
  1. Indications
    1. Acute Cholecystitis
  2. Technique
    1. Examiner palpates the abdominal RUQ (deep subcostal palpation)
    2. Patient takes a deep breath
  3. Interpretation
    1. Positive test if the patient has increased pain or suddenly halts their inspiration due to pain (inspiratory arrest)
    2. Suggests Acute Cholecystitis when present
  4. Efficacy
    1. General patients
      1. Positive Likelihood Ratio: 5.0
      2. Negative Likelihood Ratio: 0.4
      3. Test Sensitivity: 65%
      4. Test Specificity: 87%
    2. Older patients
      1. Positive Likelihood Ratio: 2.3
      2. Negative Likelihood Ratio: 0.66
      3. Test Sensitivity: 48%
      4. Test Specificity: 79%
  5. References
    1. Trowbridge (2003) JAMA 289(1): 80-6 [PubMed]

Murphy's sign (C0277977)

Concepts Sign or Symptom (T184)
SnomedCT 53566005
English abdomen Murphy's sign, Murphy's sign (physical finding), Murphy's sign was observed, Murphy sign, murphy's sign, murphy's signs, Murphy's sign, Murphy's sign (finding)
Spanish signo de Murphy (hallazgo), signo de Murphy
Derived from the NIH UMLS (Unified Medical Language System)

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