Rheumatology Book


Mycophenolate mofetil

Aka: Mycophenolate mofetil
  1. Indications
    1. Refractory Rheumatoid Arthritis
  2. Mechanism
    1. Mycophenolic acid (MPA) derivative
    2. Reversibly inhibits inosine monophosphate dehydrogenase (IMPDH)
    3. Primarily effects T Cell and B Cell proliferation and Antibody production
  3. Dosing
    1. Dose: 500-1000 mg twice daily
  4. Adverse effects
    1. Infection
    2. Malignancy (e.g. skin cancer, Lymphoma)
    3. Neutropenia
    4. Gastrointestinal Bleeding
    5. Nausea or Vomiting
  5. Monitoring
    1. PPD before starting therapy
    2. Complete Blood Count
      1. Obtain baseline
      2. Obtain weekly for first month, twice monthly for next 2 months and then monthly

You are currently viewing the original 'fpnotebook.com\legacy' version of this website. Internet Explorer 8.0 and older will automatically be redirected to this legacy version.

If you are using a modern web browser, you may instead navigate to the newer desktop version of fpnotebook. Another, mobile version is also available which should function on both newer and older web browsers.

Please Contact Me as you run across problems with any of these versions on the website.

Navigation Tree