Nephrology Book



Aka: Hypoxia, Hypoxemia
  1. See Also
    1. PaO2
    2. Arterial Blood Gas
    3. ABG Interpretation
    4. A-a Gradient
    5. Dyspnea
  2. Definition
    1. Hypoxia or Hypoxemia
      1. PaO2 <70 to 80 mmHg
  3. Causes
    1. Respiratory Failure
      1. Pulmonary Edema
      2. Pneumonia
      3. Asthma
      4. Chronic Obstructive Lung Disease (COPD)
      5. Pneumothorax
      6. Pulmonary Embolism
      7. Acute Respiratory Distress Syndrome
      8. Acute Eosinophilic Pneumonia
      9. Hypersensitivity pneumonitis
    2. Cardiogenic Shock
      1. Congestive Heart Failure
      2. Cardiomyopathy
      3. Pericardial Effusion (Cardiac Tamponade)
      4. Aortic Stenosis
      5. Mitral Stenosis
    3. Miscellaneous Causes
      1. Anemia
      2. Decreased FIO2 of inspired air (high altitude)
      3. Cyanide Poisoning
      4. Salicylate Toxicity
  4. Causes: Hypoxia or Hypoxemia (PaO2 <70 to 80 mmHg)
    1. See Hypoxemia
  5. Symptoms
    1. Dyspnea
  6. Signs
    1. Cyanosis
    2. Tachycardia
    3. Tachypnea
    4. Mental status changes
      1. Acute: Altered Level of Consciousness
      2. Chronic: Fatigue, drowsy, inattentive
    5. Oxygen Saturation (O2 Sat) decreased
      1. Usually correlates with PaO2
        1. However, relationship is not linear (See O2 Sat)
        2. Not sensitive for increased A-a Gradient
      2. Conditions where O2 Sat low despite normal PaO2
        1. Carbon Monoxide Poisoning
        2. Methemoglobinemia or other abnormal Hemoglobin
  7. Evaluation and Management
    1. See Dyspnea
    2. See Respiratory Failure

Hypoxia (C0242184)

Definition (NCI_NCI-GLOSS) A condition in which there is a decrease in the oxygen supply to a tissue. In cancer treatment, the level of hypoxia in a tumor may help predict the response of the tumor to the treatment.
Definition (NCI) A decrease in the amount of oxygen in the body. Symptoms range from mild (impaired judgment, memory loss, impaired motor coordination) to severe (seizures and coma).
Definition (NCI_CTCAE) A disorder characterized by a decrease in the level of oxygen in the body.
Definition (CSP) reduction of oxygen supply to tissue below physiological level.
Concepts Pathologic Function (T046)
MSH D000860
SnomedCT 30869003, 389086002
LNC LA17396-5
English Deficiencies, Oxygen, Deficiency, Oxygen, Hypoxias, Oxygen Deficiencies, Oxygen Deficiency, OXYGEN DEFIC, DEFIC OXYGEN, hypoxia, hypoxia (diagnosis), oxygen deficiency, HYPOXIA, hypoxic, Decreased oxygen supply, Hypoxic, Hypoxia (disorder), deficiency; oxygen, oxygen; deficiency, Hypoxia
French HYPOXIE, Hypoxique, Déficit en oxygène, Hypoxie
Portuguese HIPOXIA, Hipóxico, Hipóxia, Hipoxia, Deficiência de Oxigênio
Spanish HIPOXIA, Hipóxico, Hipoxia, aporte de oxígeno disminuido, hipoxia (trastorno), hipoxia, Deficiencia de Oxígeno
Dutch hypoxisch, deficiëntie; zuurstof, zuurstof; deficiëntie, hypoxie, Hypoxie, Zuurstoftekort
German hypoxisch, Hypoxie, HYPOXIE, Sauerstoffmangel
Italian Ipossico, Carenza di ossigeno, Ipossia
Japanese 低酸素症, 低酸素性, テイサンソショウ, テイサンソセイ
Czech hypoxie, Hypoxie, Hypoxický, nedostatek kyslíku
Hungarian Hypoxiás, Hypoxia
Norwegian Hypoksi
Derived from the NIH UMLS (Unified Medical Language System)

Hypoxemia (C0700292)

Definition (NCI) A finding indicating decreased oxygen levels in the blood.
Definition (NCI_NCI-GLOSS) A condition in which there is not enough oxygen in the blood.
Concepts Finding (T033)
MSH D000860, D000859
ICD9 799.02
ICD10 R09.02
SnomedCT 207551003, 30869003, 389087006, 356601000009102
English Hypoxemia, HYPOXAEMIA, HYPOXEMIA, [D]Hypoxaemia, [D]Hypoxemia, [D]Hypoxemia (context-dependent category), Hypoxemias, arterial hypoxaemia, hypoxemias, hypoxaemia, arterial hypoxemia, hypoxemia, hypoxemia (diagnosis), [D]Hypoxemia (situation), Blood oxygen decreased, Hypoxemia (finding), Blood oxygen level below normal, Arterial hypoxaemia, Arterial hypoxemia, Hypoxaemia, Hypoxemia (disorder)
French HYPOXEMIE, Hypoxémia, Hypoxémie
Portuguese HIPOXEMIA, Hipoxemia
Spanish HIPOXEMIA, Hipoxemia, [D]hipoxemia (categoría dependiente del contexto), [D]hipoxemia (situación), [D]hipoxemia, hipoxemia (trastorno), hipoxemia
Dutch hypoxemie, Hypoxemie
German Hypoxaemie, Hypoxämie, HYPOXAEMIE
Italian Ipossiemia, Ipossemia
Czech hypoxémie, Hypoxemie
Japanese テイサンソケッショウ, 低酸素血症
Hungarian Hypoxaemia
Norwegian Hypoksemi
Derived from the NIH UMLS (Unified Medical Language System)

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