//fpnotebook.com/
Norpramin
Aka: Norpramin, Desipramine, Pertofrane- Dosing
- Start: 50 mg PO qd for 3 days
- Next: 50 mg PO bid for 3 days
- Next: 100 PO qhs for 3 days
- Therapeutic dose: 150 PO qhs
- Maximum: 250 mg PO qhs
- Pharmacokinetics
- Serum Half Life: 21 hours
- Therapeutic plasma level: 125 to 300
- Adverse effects
- See Tricyclic Antidepressants
- Much less adverse effects than tertiary amines
- Moderate adverse effects
- Precautions
- See Tricyclic Antidepressants
- Serious cardiotoxicity in overdosage
- Advantages
- Activating
- Inexpensive
- Attention Deficit Hyperactivity Disorder effect
Medication Costs | ||
---|---|---|
desipramine (on 5/17/2017 at Medicaid.Gov Pharmacy Drug pricing) | ||
DESIPRAMINE 10 MG TABLET | Generic | $0.64 each |
DESIPRAMINE 100 MG TABLET | Generic | $3.75 each |
DESIPRAMINE 25 MG TABLET | Generic | $1.08 each |
DESIPRAMINE 50 MG TABLET | Generic | $2.10 each |
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. |
Desipramine (C0011685) |
|
---|---|
Definition (NCI) | An active metabolite of imipramine, a tertiary amine and a synthetic tricyclic derivative of the antidepressant. Desipramine enhances monoamine neurotransmission in certain areas of the brain by inhibiting the re-uptake of noradrenaline and serotonin at the noradrenergic and serotoninergic nerve endings, respectively. It also induces sedation through histamine 1 receptor blockage and hypotension through beta-adrenergic blockage. |
Definition (MSH) | A tricyclic dibenzazepine compound that potentiates neurotransmission. Desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport. This compound also possesses minor anticholinergic activity, through its affinity to muscarinic receptors. |
Definition (CSP) | tricyclic dibenzazepine compound that potentiates neurotransmission; desipramine selectively blocks reuptake of norepinephrine from the neural synapse, and also appears to impair serotonin transport; this compound also possesses minor anticholingeric activity, through its affinity to muscarinic receptors. |
Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
MSH | D003891 |
SnomedCT | 33378002, 372705002 |
LNC | LP16103-1, MTHU004929 |
English | Desipramine, Demethylimipramine, Desmethylimipramine, 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-methyl-, desmethylimipramine, Desipramine [Chemical/Ingredient], desipramine, DESIPRAMINE, Desipramine (product), Desipramine (substance) |
Swedish | Desipramin |
Czech | desipramin |
Finnish | Desipramiini |
Russian | DEZIPRAMIN, DESMETILIMIPRAMIN, DEZIPRAMINGIDROKHLORID, ДЕЗИПРАМИН, ДЕЗИПРАМИНГИДРОХЛОРИД, ДЕСМЕТИЛИМИПРАМИН |
Japanese | デシプラミン, デスメチルイミプラミン |
Italian | Desmetilimipramina, Demetilimipramina, Desipramina |
Croatian | DESIPRAMIN |
Polish | Dezypramina |
Spanish | desipramina (producto), desipramina (sustancia), desipramina, Desipramina, Desmetilimipramina |
French | Désipramine |
German | Desipramin, Desmethylimipramin |
Portuguese | Desipramina, Desmetilimipramina |
Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Pertofrane (C0031232) |
|
---|---|
Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
MSH | D003891 |
English | Pertofrane, Pertofran, Novartis Brand of Desipramine Hydrochloride, Pertrofran, Rhône Poulenc Rorer Brand of Desipramine Hydrochloride, Rhône-Poulenc Rorer Brand of Desipramine Hydrochloride |
Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Norpramin (C0701352) |
|
---|---|
Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
MSH | D003891 |
Croatian | NORPRAMIN |
English | norpramin, Norpramin, Aventis Behring Brand of Desipramine Hydrochloride, Aventis Brand of Desipramine Hydrochloride |
Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
You are currently viewing the original 'fpnotebook.com\legacy' version of this website. Internet Explorer 8.0 and older will automatically be redirected to this legacy version.
If you are using a modern web browser, you may instead navigate to the newer desktop version of fpnotebook. Another, mobile version is also available which should function on both newer and older web browsers.
Please Contact Me as you run across problems with any of these versions on the website.