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Meprobamate
Aka: Meprobamate, Equanil- Class
- Propanediol Sedative
- Indications
- Anxiety
-
Pharmacokinetics
- Half Life: 6-17h
- Dosing
- Max Daily Dose: 1600 mg qd
| Medication Costs | ||
|---|---|---|
| meprobamate (on 5/18/2016 at Medicaid.Gov Pharmacy Drug pricing) | ||
| MEPROBAMATE 200 MG TABLET | Generic | $1.49 each |
| MEPROBAMATE 400 MG TABLET | Generic | $3.34 each |
| FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. | ||
Meprobamate (C0025386) |
|
|---|---|
| Definition (NCI) | A carbamate derivate with hypnotic, anti-anxiety, sedative, anticonvulsant and some indirect muscle relaxant properties. Although the exact mechanism of meprobamate is largely unknown, it appears to act as a depressant at multiple sites in the central nervous system, mostly likely through the GABAergic neurotransmitter system, including the thalamus and limbic system. |
| Definition (MSH) | A carbamate with hypnotic, sedative, and some muscle relaxant properties, although in therapeutic doses reduction of anxiety rather than a direct effect may be responsible for muscle relaxation. Meprobamate has been reported to have anticonvulsant actions against petit mal seizures, but not against grand mal seizures (which may be exacerbated). It is used in the treatment of ANXIETY DISORDERS, and also for the short-term management of INSOMNIA but has largely been superseded by the BENZODIAZEPINES. (From Martindale, The Extra Pharmacopoeia, 30th ed, p603) |
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | D008620 |
| SnomedCT | 387395007, 70864001 |
| LNC | LP16187-4, MTHU011050 |
| English | Meprobamate, 1,3-Propanediol, 2-methyl-2-propyl-, dicarbamate, 1,3-Propanediol, 2-methyl-2-propyl-, Dicarbamate, Miltown 600, Neuramate, meprobamate (medication), meprobamate, MEPROBAMATE, Meprobamate [Chemical/Ingredient], Meprobamate (product), Meprobamate (substance) |
| Swedish | Meprobamat |
| Czech | meprobamát |
| Finnish | Meprobamaatti |
| Russian | MEPROBAMAT, МЕПРОБАМАТ |
| Japanese | メプロバメート |
| Croatian | MEPROBAMAT |
| Polish | Meprobamat, Miltown, Equanil |
| Spanish | Equanil, meprobamato (producto), meprobamato (sustancia), meprobamato, Meprobamato |
| Portuguese | Equanil, Meprobamato |
| French | Méprobamate |
| German | Meprobamat |
| Italian | Meprobamato |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Equanil (C0591455) |
|
|---|---|
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | D008620 |
| English | equanil, Equanil, Meprobamate Wyeth Brand, Sanofi Synthelabo Brand of Meprobamate, Wyeth Brand of Meprobamate |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
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