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Major Depression Diagnosis

Aka: Major Depression Diagnosis, DSM-5 Criteria for Major Depressive Disorder, DSM-V Criteria for Major Depressive Episode
  1. See Also
    1. Major Depression
  2. Diagnosis: Criteria to diagnose Major Depression
    1. Symptoms lasting at least 2 weeks, with each symptom persisting for most of each day, nearly everyday
      1. A total of 5 positive symptoms are required for diagnosis of Major Depression
      2. At least 1 of the following two major symptoms (most of each day, nearly everyday)
        1. Depressed mood
          1. Patient reports they feel sad, empty or helpless (or others observe this, e.g. crying)
          2. Irritable mood meets criteria in adolescents and children
        2. Reduction in pleasure or interest
          1. Diminished pleasure or participation in all or nearly all activities
      3. At least 4 (or 3 if both major symptoms present) of the following (most of each day, nearly everyday)
        1. Unintentional Weight Loss or weight gain
          1. Significant unintended weight change (e.g. >5%) or appetite change
        2. Insomnia or Hypersomnia
        3. Psychomotor Agitation or retardation
          1. Restlessness or slowed so significantly as to be recognized by others
        4. Fatigue or loss of energy
        5. Sense of worthlessness, or excessive or inappropriate guilt
        6. Decreased concentration or indecisiveness
        7. Recurrent thoughts of death or Suicidality (with or without a plan)
    2. Significantly impaired social and occupation function
    3. Symptoms do not meet criteria for other diagnosis that better explains symptoms
      1. No history of non-drug induced mania or Hypomania
      2. No mixed Bipolar Disorder
      3. No schizoaffective disorder or Schizophrenia
      4. No Delusional disorder
    4. Not due to significant acute loss that would better explain symptoms
      1. Not due to Bereavement, financial ruin or natural disaster
      2. Major Depression may be diagnosed if criteria met beyond the acute stressors
    5. No secondary causes
      1. Not caused by general medical illness (e.g. Hypothyroidism)
      2. Not a result of medication use
      3. Not a result of Alcohol Abuse or Drug Abuse
  3. Diagnosis: Cluster 1 (Physical, neurovegetative symptoms)
    1. Sleep Disturbance
    2. Appetite or weight change
    3. Attention or concentration problem
    4. Energy level change or Fatigue
    5. Psychomotor disturbance
  4. Diagnosis: Cluster 2 (Psychologic, psychosocial symptoms)
    1. Depressed mood
    2. Reduction in pleasure or interest
    3. Feelings of guilt
    4. Suicidal thoughts
  5. References
    1. (2013) DSM-V, APA, Washington, D.C.
    2. (2000) DSM-IV, APA, Washington, D.C.

Major Depressive Disorder (C1269683)

Definition (MSH) Marked depression appearing in the involution period and characterized by hallucinations, delusions, paranoia, and agitation.
Definition (PSY) Affective disorder marked by dysphoric mood, inactivity, lack of interest, insomnia, feelings of worthlessness, diminished ability to think, and thoughts of suicide. Use DEPRESSION (EMOTION) for nonclinical depression.
Definition (CSP) one or more periods of depression in the absence of history of manic or hypomanic episodes; chronic type lasts 2 or more years; melancholic type is more severe, has vegetative signs, and responds well to somatic therapy.
Concepts Mental or Behavioral Dysfunction (T048)
MSH D003865
ICD10 F32.9
SnomedCT 370143000, 35489007
English Disorder, Major Depressive, Disorders, Major Depressive, Major Depressive Disorders, MDD, MAJOR DEPRESSIVE DISORDER, DEPRESSIVE DIS MAJOR, MAJOR DEPRESSIVE DIS, Major depressive disorder NOS, Major depressive illness, Major depression NOS, Depressive Disorder, Major [Disease/Finding], major depressive illness, major depressive disorder, major depression, Major depressive disorder (diagnosis), Major depression, Major depressive disorder (disorder), Major depressive disorder, Major depression, NOS, Major depressive disorder, NOS, Depressive Disorder, Major, Depressive Disorders, Major, Major Depressive Disorder, Major Depression
Dutch depressieve ziekte, depressieve stoornis NAO, major depression, Depressieve stoornis, ernstige, Ernstige depressieve stoornis, Involutiepsychose, Melancholie, involutionele, Parafrenie, involutionele, Psychose, involutionele, Involutiedepressie, Involutionele depressie
French Syndrome dépressif majeur SAI, Épisode dépressif majeur, Dépression grave, Grave dépression, Dépression majeure, Trouble dépressif majeur
German Major Depression NNB, schwere depressive Krankheit, Endogene Depression, Involutionsdepression, Melancholie, Involutions-, Paraphrenie, Involutions-, Psychose, Involutions-, Depressive Störung, majore, Majore depressive Störung
Italian Depressione maggiore NAS, Malattia depressiva maggiore, Depressione maggiore, Disturbo depressivo maggiore
Portuguese Doença depressiva major, Perturbação depressiva major NE, Depressão grave, Transtorno Depressivo Maior
Spanish Trastorno depresivo mayor NEOM, Enfermedad depresiva mayor, depresión mayor, trastorno depresivo mayor (trastorno), trastorno depresivo mayor, Depresión mayor, Trastorno Depresivo Mayor
Japanese 大うつ病NOS, オオウツビョウ, ダイウツビョウ, ダイウツビョウNOS, うつ病-退行期, 大うつ病性障害, 大鬱病, うつ病-更年期, 大うつ病, 初老期うつ病, 更年期うつ病, 更年期鬱病, 精神病-更年期, 退行期うつ病, 退行期パラフレニー, 退行期メランコリア, 退行期精神病, 鬱病-更年期, パラフレニー-退行期, 更年期うつ状態, 更年期メランコリー, 更年期精神病, 更年期鬱状態, 精神病-退行期, 退行期鬱病
Swedish Involutionsdepression
Czech psychóza involuční, deprese involuční, depresivní porucha unipolární, melancholie involuční, parafrenie involuční, Velké depresivní onemocnění, Velká deprese, Velká depresivní porucha NOS
Finnish Laaja-alainen masentuneisuushäiriö
Polish Wielkie zaburzenie depresyjne, Zaburzenie depresyjne wielkie, Ciężkie zaburzenie depresyjne, Depresja wielka, Parafrenia inwolucyjna, Depresja głęboka, Epizod depresji dużej, Depresja inwolucyjna
Hungarian Major depressiós betegség, Major depressio, Major depressiós zavar k.m.n.
Norwegian Depresjon, alvorlig, Markert depresjon, Depresjon, markert, Alvorlig depresjon, Markant depressiv forstyrrelse
Derived from the NIH UMLS (Unified Medical Language System)

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