//fpnotebook.com/
Arachidonic Acid Derivatives
Aka: Arachidonic Acid Derivatives, Arachidonic Acid, Eicosanoid, Prostaglandin, Thromboxane, Leukotriene- See Also
- Definitions
- Arachidonic Acid
- Arachidonic Acid is a polyunsaturated Essential Fatty Acid present in human fat, liver, brain and glandular organs
- Derived from dietary Linoleic Acid
- Precursor of Prostaglandins, prostacyclins, Thromboxanes, and Leukotrienes.
- Arachidonic Acid
- Physiology: Arachidonic Acid Derivatives (Eicosanoids)
- General
- Derived from Arachidonic Acid via cyclooxygenase pathway
- Basic structure is a 5 carbon ring "head" with two 6 to 9 carbon chain "legs"
- Functions vary by specific molecule, but function in general is summarized here
- Thromboxanes
- Increase Platelet aggregation
- Leukotrienes
- Leukocyte chemotaxis
- Prostacyclin
- Inhibits Platelet aggregation
- Vasodilates
- Prostaglandins
- Some Prostaglandins contract Smooth Muscle (e.g. Vasoconstriction, bronchoconstriction, uterine contraction)
- Some Prostaglandins increase inflammatory response as well as pain and fever
- General
Arachidonic Acid (C0003695) |
|
|---|---|
| Definition (NCI) | An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.(ChemID Plus) |
| Definition (NCI_CRCH) | Polyunsaturated fatty acid with 20 carbons and 4 double bonds at the 6th, 9th, 12th and 15th carbons from the methyl end. |
| Definition (MSH) | An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. |
| Concepts | Eicosanoid (T111) |
| MSH | D016718 |
| SnomedCT | 3792001 |
| English | 5,8,11,14-Eicosatetraenoic acid, (all-Z)-, (all-Z)-5,8,11,14-Eicosatetraenoic acid, (all-Z)-5,8,11,14-Eicosatetraenoic Acid, Vitamin F, Eicosatetraenoic acid, Eicosatetranoic acid, vitamin F, Arachidonic Acid, Arachidonic Acid [Chemical/Ingredient], vitamin f, acid arachidonic, ARACHIDONIC ACID, arachidonic acid, All-cis-icosa-5,8,11,14-tetraenoic acid, Fatty Acid 20:4 n-6, Arachidonic acid, 5,8,11,14-Eicosatetraenoic acid, AA - Arachidonic acid, Arachidonic acid (substance) |
| Swedish | Arakidonsyra |
| Czech | kyselina arachidonová, kyselina arašidonová |
| Finnish | Arakidonihappo |
| Russian | ARAKHIDONOVAIA KISLOTA, АРАХИДОНОВАЯ КИСЛОТА |
| Japanese | エイコサテトラエン酸, アラキドン酸, 5,8,11,14-エイコサテトラエン酸, 5,8,11,14-イコサテトラエン酸, ビタミンF |
| Croatian | ARAHIDONSKA KISELINA |
| Polish | Kwas arachidonowy |
| Spanish | ácido 5, 8, 11, 14 - eicosatetraenoico, ácido araquidónico (sustancia), ácido araquidónico, Ácido Araquidónico |
| French | Acide arachidonique, Arachidonique, acide |
| German | Arachidonsäure |
| Italian | Acido arachidonico |
| Portuguese | Ácido Araquidônico |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Arachidonic Acids (C0003701) |
|
|---|---|
| Concepts | Eicosanoid (T111) |
| MSH | D001095 |
| English | Acids, Arachidonic, Arachidonic Acids, Arachidonic Acids [Chemical/Ingredient] |
| Swedish | Arakidonsyror |
| Czech | kyseliny arachidonové |
| Finnish | Arakidonihapot |
| Russian | EIKOZATETRAENOVYE KISLOTY, ARAKHIDONOVYE KISLOTY, АРАХИДОНОВЫЕ КИСЛОТЫ, ЭЙКОЗАТЕТРАЕНОВЫЕ КИСЛОТЫ |
| Croatian | Not Translated[Arachidonic Acids] |
| Polish | Kwasu arachidonowego pochodne |
| French | Acides arachidoniques, Arachidoniques, acides |
| German | Arachidonsäuren |
| Italian | Acidi arachidonici |
| Portuguese | Ácidos Araquidônicos |
| Spanish | Ácidos Araquidónicos |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Eicosanoids (C0013725) |
|
|---|---|
| Definition (MSHCZE) | Skupina biologicky aktivních látek vznikajících z arachidonové kyseliny. Mají charakter tkáňových hormonů. Viz leukotrieny, prostaglandiny, tromboxany, prostanoidy. (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ ) |
| Definition (MSH) | A class of compounds named after and generally derived from C20 fatty acids (EICOSANOIC ACIDS) that includes PROSTAGLANDINS; LEUKOTRIENES; THROMBOXANES, and HYDROXYEICOSATETRAENOIC ACIDS. They have hormone-like effects mediated by specialized receptors (RECEPTORS, EICOSANOID). |
| Definition (CSP) | class of compounds named after and generally derived from C20 fatty acids (eicosanoic acids) that includes prostaglandins, leukotrienes, thromboxanes, and hydroxyeicosatetraenoic acids; they have hormone-like effects mediated by specialized receptors (eicosanoid receptors). |
| Concepts | Eicosanoid (T111) |
| MSH | D015777 |
| SnomedCT | 418534004 |
| English | Eicosanoids, eicosanoid, Eicosanoids [Chemical/Ingredient], eicosanoids, icosanoid, Icosanoids, Eicosanoid, Eicosanoid (substance) |
| Spanish | eicosanoide (sustancia), eicosanoide, Eicosanoides, Icosanoides |
| Swedish | Eikosanoider |
| Finnish | Eikosanoidit |
| Italian | Icosanoidi, Eicosanoidi |
| Russian | EIKOZANOIDY, ЭЙКОЗАНОИДЫ |
| French | Icosanoïdes, Éicosanoïdes |
| Croatian | EIKOZANOIDI |
| Polish | Eikozanoidy, Eikosanoidy |
| Japanese | イコサノイド, エイコサノイド |
| Portuguese | Eicosanoides, Icosanoides |
| Czech | eikosanoidy, ikosanoidy |
| German | Eicosanoide, Icosanoide |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Leukotrienes (C0023545) |
|
|---|---|
| Definition (MSH) | A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system. |
| Definition (CSP) | family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway; participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation; have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system. |
| Concepts | Biologically Active Substance (T123) , Eicosanoid (T111) |
| MSH | D015289 |
| SnomedCT | 12194000 |
| English | Leukotrienes, Leukotrienes [Chemical/Ingredient], leukotriene, leukotrienes, Leukotriene (substance), Leukotriene, Leukotriene, NOS |
| Swedish | Leukotriener |
| Czech | leukotrieny |
| Finnish | Leukotrieenit |
| Russian | LEIKOTRIENY, ЛЕЙКОТРИЕНЫ |
| French | Leucotriènes |
| Croatian | LEUKOTRIENI |
| Polish | Leukotrieny |
| Spanish | leucotrieno (sustancia), leucotrieno, Leucotrienos |
| German | Leukotriene |
| Italian | Leucotrieni |
| Portuguese | Leucotrienos |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Prostaglandins (C0033554) |
|
|---|---|
| Definition (CHV) | a kind of hormone |
| Definition (CHV) | a kind of hormone |
| Definition (CHV) | a kind of hormone |
| Definition (CHV) | a kind of hormone |
| Definition (NCI_NCI-GLOSS) | One of several hormone-like substances made by the body. Different PGs control blood pressure, contraction of smooth muscles, and other processes within tissues where they are made. Certain PGs are being studied as cancer biomarkers. |
| Definition (MSH) | A group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via the cyclooxygenase pathway. They are extremely potent mediators of a diverse group of physiological processes. |
| Definition (PSY) | Physiologically potent compounds of ubiquitous occurrence formed from essential fatty acids and affecting the nervous system, female reproductive organs, and metabolism. |
| Definition (CSP) | group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via the cyclooxygenase pathway; extremely potent mediators of a diverse group of physiological processes. |
| Concepts | Eicosanoid (T111) , Biologically Active Substance (T123) , Pharmacologic Substance (T121) |
| MSH | D011453 |
| SnomedCT | 373688002, 109059001, 26351002, 350067007 |
| LNC | LP15827-6, LP19203-6, MTHU013657, MTHU007142 |
| English | Prostanoids, PROSTAGLANDINS, prostaglandins, prostaglandins (medication), [HS875] PROSTAGLANDINS, Prostaglandins [Chemical/Ingredient], prostaglandin, prostanoids, prostanoid, Prostaglandins, Prostaglandin agent (substance), Prostaglandin preparation, Prostaglandin agent, Prostaglandin preparation (product), PG, Prostaglandin, Prostaglandin product, PG - Prostaglandin, Prostaglandin (substance), Prostaglandin product (product), prostaglandin agent, prostoglandin agent, Prostaglandin, NOS, Prostaglandin preparation (substance), Prostaglandin product (substance) |
| Swedish | Prostaglandiner |
| Czech | prostaglandiny, prostanoidy |
| Finnish | Prostaglandiinit |
| Russian | PROSTAGLANDINY, ПРОСТАГЛАНДИНЫ |
| Japanese | プロスタグランジン, プロスタグランディン, プロスタノイド |
| Spanish | producto con prostaglandina (producto), prostaglandina (producto), producto con prostaglandina, agente con prostaglandina, preparado de prostaglandina, preparado de prostaglandina (producto), agente con prostaglandina (sustancia), preparado de prostaglandina (sustancia), prostaglandina (sustancia), prostaglandina, producto (producto), prostaglandina, producto (sustancia), prostaglandina, producto, prostaglandina, Prostaglandinas |
| French | Prostanoïdes, Prostaglandines |
| Italian | Prostanoidi, Prostaglandine |
| Croatian | PROSTAGLANDINI |
| Polish | Prostaglandyny |
| German | Prostaglandine |
| Portuguese | Prostaglandinas |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Thromboxanes (C0040061) |
|
|---|---|
| Definition (MSH) | Physiologically active compounds found in many organs of the body. They are formed in vivo from the prostaglandin endoperoxides and cause platelet aggregation, contraction of arteries, and other biological effects. Thromboxanes are important mediators of the actions of polyunsaturated fatty acids transformed by cyclooxygenase. |
| Definition (CSP) | physiologically active compounds found in many organs of the body, formed in vivo from the prostaglandin endoperoxides and causing platelet aggregation, contraction of arteries, and other biological effects; important mediators of the actions of polyunsaturated fatty acids transformed by cyclooxygenase. |
| Concepts | Eicosanoid (T111) , Biologically Active Substance (T123) |
| MSH | D013931 |
| SnomedCT | 80946001 |
| LNC | LP31748-4 |
| English | Thromboxanes, Thromboxanes [Chemical/Ingredient], thromboxanes, thromboxane, Thromboxane (substance), Thromboxane, Thromboxane, NOS |
| Swedish | Tromboxaner |
| Czech | thromboxany |
| Finnish | Tromboksaanit |
| Russian | TROMBOKSANY, ТРОМБОКСАНЫ |
| Polish | Tromboksany, TX |
| Croatian | Tromboksani |
| Spanish | tromboxano (sustancia), tromboxano, Tromboxanos |
| French | Thromboxanes |
| German | Thromboxane |
| Italian | Trombossani |
| Portuguese | Tromboxanos |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
You are currently viewing the original 'fpnotebook.com\legacy' version of this website. Internet Explorer 8.0 and older will automatically be redirected to this legacy version.
If you are using a modern web browser, you may instead navigate to the newer desktop version of fpnotebook. Another, mobile version is also available which should function on both newer and older web browsers.
Please Contact Me as you run across problems with any of these versions on the website.