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Naproxen
Aka: Naproxen, Naprosyn, Anaprox, Aleve- Class
- NSAID in the propionic acid class
- Pharmacokinetics
- Naproxen Sodium has faster action onset than Naproxen
- Dosing
- Naproxen (Naprosyn) 250-500 mg orally twice daily prn
- Naproxen Sodium (Anaprox, Aleve) 550 mg orally twice daily prn
- Adverse Effects
- See NSAID Gastrointestinal Adverse Effects
- See NSAID Renal Adverse Effects
- Bleeding risk (inhibits Platelet aggregation)
- Naprosyn increases risk almost as much as Aspirin
| Medication Costs | ||
|---|---|---|
| Naproxen (on 6/18/2017 at Walmart.com) | ||
| Naproxen 375mg | #60 tablets for $4.00 | $0.07 each |
| Naproxen 375mg | #180 tablets for $10.00 | $0.06 each |
| Naproxen 500mg | #60 tablets for $4.00 | $0.07 each |
| Naproxen 500mg | #180 tablets for $10.00 | $0.06 each |
| naproxen (on 5/17/2017 at Medicaid.Gov Pharmacy Drug pricing) | ||
| NAPROXEN 125 MG/5 ML SUSPEN | Generic | $0.74 per ml |
| NAPROXEN 250 MG TABLET | Generic | $0.04 each |
| NAPROXEN 375 MG TABLET | Generic | $0.06 each |
| NAPROXEN 500 MG TABLET | Generic | $0.06 each |
| NAPROXEN DR 375 MG TABLET | Generic | $0.14 each |
| NAPROXEN DR 500 MG TABLET | Generic | $0.20 each |
| NAPROXEN SOD CR 500 MG TABLET | Generic | $12.83 each |
| NAPROXEN SOD ER 500 MG TABLET | Generic | $12.83 each |
| NAPROXEN SODIUM 220 MG TABLET | Generic OTC | $0.06 each |
| NAPROXEN SODIUM 275 MG TAB | Generic | $1.12 each |
| NAPROXEN SODIUM 550 MG TAB | Generic | $1.28 each |
| NAPROXEN SODIUM DS 550 MG TAB | Generic | $1.28 each |
| FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. | ||
Naproxen (C0027396) |
|
|---|---|
| Definition (CHV) | a drug that relieves pain, inflammation, and fever |
| Definition (NCI_NCI-GLOSS) | A drug used to treat mild pain and the symptoms of arthritis and several other conditions. It is also being studied in the treatment of bone pain in patients with cancer. Naprosyn stops the body from making substances that cause pain and inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID) and a type of cyclooxygenase inhibitor. |
| Definition (NCI) | A propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Naproxen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of naproxen. Naproxen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. |
| Definition (MSH) | An anti-inflammatory agent with analgesic and antipyretic properties. Both the acid and its sodium salt are used in the treatment of rheumatoid arthritis and other rheumatic or musculoskeletal disorders, dysmenorrhea, and acute gout. |
| Definition (CSP) | 6-methoxy-alpha-methyl-2-naphthaleneacetic acid; nonsteroidal antiinflammatory drug (NSAID); acts by inhibiting cyclooxygenase and thus prostaglandin synthesis; tocolytic oxytocin antagonist. |
| Definition (PDQ) | A propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Naproxen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of naproxen. Naproxen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40222&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40222&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C680" NCI Thesaurus) |
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | D009288 |
| SnomedCT | 363614005, 11847009, 372588000 |
| LNC | LP16215-3, MTHU015374 |
| English | Methoxypropiocin, MNPA, Naproxen, 2-Naphthaleneacetic acid, 6-methoxy-alpha-methyl-, (S)-, d-2-(6-Methoxy-2-naphthyl)propionic Acid, 6-Methoxy-alpha-methyl-2-naphthaleneacetic Acid, naproxen, NAPROXEN, naproxen (medication), non-prescription naproxen, non-prescription naproxen (medication), Naproxen [Chemical/Ingredient], Naproxen product, Naproxen product (substance), Naproxen (product), Naproxen (substance) |
| Swedish | Naproxen |
| Czech | naproxen |
| Finnish | Naprokseeni |
| Russian | NAPROKSEN, НАПРОКСЕН |
| Japanese | ナプロキセン |
| Spanish | Naproxeno, Naproxen, naproxeno (producto), naproxeno (sustancia), naproxeno |
| Polish | Naproksen |
| French | Naproxène |
| German | Naproxen |
| Italian | Naproxene |
| Portuguese | Naproxeno |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Anaprox (C0699095) |
|
|---|---|
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | D009288 |
| English | anaprox, Anaprox |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Naprosyn (C0700017) |
|
|---|---|
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | D009288 |
| English | naprosyn, naprosin, Naprosin, Naprosyn |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Aleve (C0718343) |
|
|---|---|
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | D009288 |
| English | aleve, Aleve |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
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