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Feverfew
Aka: Feverfew, Tanacetum parthenium
- Indications (Purported uses)
- Migraine Headache prevention
- Efficacy
- Some studies support benefit for Migraine prevention
- No benefit in Rheumatoid Arthritis
- Mechanism
- Inhibits prostaglandin synthesis
- Serotonin antagonist
- Inhibits Platelet aggregation
- Dosing
- Standard extract 125 mg (at least 0.2% parthenolide)
- Adverse Effects
- Bleeding Diathesis due to Platelet Dysfunction
- Contraindications
- Pregnancy
- Feverfew may induce Menstruation
- Concurrent Anticoagulant use or peri-operative
- Feverfew increases bleeding risk
- References
- Shaughnessy (1997) Fam Practice Recert 19(10):53-6
- Zink (1998) Am Fam Physician 58(5): 1133-40 [PubMed]