Pediatrics Book

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Meso-2,3-dimercaptosuccinic acid

Aka: Meso-2,3-dimercaptosuccinic acid, DMSA
  1. Indications: Lead Poisoning
    1. Low to moderate Lead Intoxication (25-49 ug/dl)
  2. Mechanism
    1. Oral lead chelating agent
  3. Dosing
    1. DMSA 10 mg/kg PO every 8 hours for 5 days
  4. Efficacy
    1. Safer than other lead chelating agents
    2. More effective for moderate Poisoning than other agents
  5. References
    1. Besunder (1995) Pediatrics 96:683-7 [PubMed]

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