Obstetrics Book

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Unconjugated Estriol

Aka: Unconjugated Estriol
  1. Indications
    1. Included in Triple Screen
  2. Physiology
    1. Normally produced at low levels by ovaries
    2. Elevated in pregnancy
      1. Produced by placenta
      2. Precursors supplied by fetus
        1. Fetal Adrenal Glands
        2. Fetal liver
  3. Increased Unconjugated Estriol
    1. Increases throughout normal pregnancy
  4. Decreased Unconjugated Estriol
    1. Trisomy 21 (Down Syndrome)
    2. Trisomy 18 (Edwards Syndrome)

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