Obstetrics Book

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AmniSure ROM Test

Aka: AmniSure ROM Test, PAMG-1 Protein Marker Test, Placental Alpha Microglobulin-1 Rapid Immunoassay
  1. See Also
    1. Vaginal Fluid Ferning
    2. Premature Rupture of Membranes
    3. Vaginal Fluid pH (Nitrazine)
    4. Vaginal Pooling
  2. Indications
    1. Evaluation for Premature Rupture of Membranes
  3. Mechanism
    1. Placental Alpha Microglobulin-1 Rapid Immunoassay (PAMG-1 Protein Marker Assay)
    2. PAMG-1 is 1000 to 10,000 times more concetrated in amniotic fluid than in cervical or vaginal secretions
  4. Technique
    1. No vaginal exam should be done prior to testing
    2. Sterile Dacron swab is placed at the posterior vaginal fornix for 1 minute
    3. Swab is placed in solvent vial for 1 minute
    4. Test strip is placed in solvent and result is available in 5 minutes
  5. Efficacy
    1. Test Sensitivity: 95.7%
    2. Test Specificity: 100%
    3. Contrast with Test Sensitivity of 78.1% for combined standard methods
      1. Vaginal Fluid Ferning
      2. Vaginal Fluid pH (Nitrazine)
      3. Vaginal Pooling
  6. References
    1. Ng (2013) Biomed Res Int 2013:587438 +PMID:24073412 [PubMed]

Alpha-1-Microglobulin.placental:ACnc:Pt:Vag:Ord (C1978245)

Concepts Clinical Attribute (T201)
LNC 50385-4
English A1 Microglob placental Vag Ql, Alpha-1-Microglobulin.placental [Presence] in Vaginal fluid, Alpha-1-Microglobulin.placental:ACnc:Pt:Vag:Ord, Alpha-1-Microglobulin.placental:Arbitrary Concentration:Point in time:Vagina:Ordinal
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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