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AmniSure ROM Test
Aka: AmniSure ROM Test, PAMG-1 Protein Marker Test, Placental Alpha Microglobulin-1 Rapid Immunoassay
- See Also
- Vaginal Fluid Ferning
- Premature Rupture of Membranes
- Vaginal Fluid pH (Nitrazine)
- Vaginal Pooling
- Indications
- Evaluation for Premature Rupture of Membranes
- Mechanism
- Placental Alpha Microglobulin-1 Rapid Immunoassay (PAMG-1 Protein Marker Assay)
- PAMG-1 is 1000 to 10,000 times more concetrated in amniotic fluid than in cervical or vaginal secretions
- Technique
- No vaginal exam should be done prior to testing
- Sterile Dacron swab is placed at the posterior vaginal fornix for 1 minute
- Swab is placed in solvent vial for 1 minute
- Test strip is placed in solvent and result is available in 5 minutes
- Efficacy
- Test Sensitivity: 95.7%
- Test Specificity: 100%
- Contrast with Test Sensitivity of 78.1% for combined standard methods
- Vaginal Fluid Ferning
- Vaginal Fluid pH (Nitrazine)
- Vaginal Pooling
- References
- Ng (2013) Biomed Res Int 2013:587438 +PMID:24073412 [PubMed]