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Early Onset Growth Restriction
Aka: Early Onset Growth Restriction, Early Onset IUGR, Symmetric IUGR, Symmetric Intrauterine Growth Retardation
- See Also
- Intrauterine Growth Retardation (IUGR)
- Asymmetric Intrauterine Growth Retardation (Asymmetric IUGR)
- Large for Gestational Age
- Epidemiology
- Early onset Fetal Growth Restriction (<32 weeks gestation) accounts for 20-30% of cases of IUGR
- Background
- IUGR is now divided into early and late onset (before or after 32 weeks gestation)
- Replaces prior symmetric vs asymmetric classification, which did not predict outcomes as well
- Early onset is more severe and progressive than late onset IUGR
- Associated with decreased umbilical artery flow in 70%
- Associated with perinatal death in 7%
- Associated Conditions
- Associated with Preeclampsia in 35% of cases
- Chromosome or genetic abnormalities in 20% of cases
- Pathophysiology
- Intrauterine Growth Retardation onset <32 weeks
- Associated with serious neurologic sequelae
- Early onset typically affects both Head and body growth
- However asymmetry is less predictive of complications than timing
- Causes
- See Intrauterine Growth Retardation
- Management
- See Intrauterine Growth Retardation (IUGR)
- References
- Westby (2021) Am Fam Physician 104(5): 486-92 [PubMed]