Neurology Book


Intranasal Dihydroergotamine

Aka: Intranasal Dihydroergotamine, Migranal
  1. Indications
    1. Migraine Abortive Management
  2. Efficacy
    1. Significant Migraine response in 30 minutes
      1. Migranal: 70%
      2. Placebo: 28%
    2. Reference
      1. Gallagher (1996) Arch Neurol 53:1285-91 [PubMed]
  3. Dosing
    1. Prepare sprayer by inserting ampule and prime pump
    2. Use one spray each nostril
    3. May repeat x1 after 15 minutes (Total dose = 2mg)
    4. Maximum use is 2 times per week
  4. Advantages
    1. Lasts longer than intranasal Imitrex
    2. Rebound Headache less common than Imitrex
      1. Rebound HeadacheIncidence: 15% within 24 hours
    3. Less expensive than Intranasal Imitrex ($16/dose)
  5. Disadvantages
    1. Does not work as fast as intranasal Imitrex
    2. More complicated to use than intranasal Imitrex
  6. Adverse Effects
    1. Rhinitis
    2. Nausea
    3. Taste perversion
Medication Costs
migranal (on 5/18/2016 at Medicaid.Gov Pharmacy Drug pricing)
MIGRANAL NASAL SPRAY Generic $375.81 per ml
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

Migranal (C0086157)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH D004087
English Dihydergot, dihydergot, migranal, Migranal (obsolete), Migranal, Dihydroergotamine Sandoz, Dihydroergotamine-Sandoz, Novartis Brand of Dihydroergotamine Mesylate, Xcel Brand 1 of Dihydroergotamine Mesylate
Derived from the NIH UMLS (Unified Medical Language System)

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