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Serotonin
Aka: Serotonin, Serotoninergic, 5-Hydroxytryptamine, 5-HT
- See Also
- Serotonin Syndrome
- Carcinoid Syndrome
- Physiology
- Neurotransmitter
- Motor control
- Pain Perception
- Sympathetic Nervous System outflow
- Synthesis from essential amino acid L-tryptophan
- Serotonin Receptors
- Serotonin-1 Receptor (5-HT-1) Activity
- Anti-depressant effect
- Serotonin-2 Receptor (5-HT-2) Activity
- Inhibits 5-HT-1 Receptor
- Causes Sexual Dysfunction
- Causes Insomnia
- Causes anxiety
- Serotonin-3 Receptor (5-HT-3) Activity
- Causes Gastrointestinal symptoms
- Causes Headache
- Medications: Increase Serotonin levels
- Increased Serotonin synthesis: L-Tryptophan
- Decrease Serotonin metabolism: MAO inhibitors
- Increase Serotonin release: Amphetamines, Cocaine
- Inhibit Serotonin uptake
- Tricyclic Antidepressants: Amitriptyline
- Selective Serotonin Reuptake Inhibitor (SSRI): Prozac
- Other: Meperidine, Dextromethorphan
- Direct Serotonin Receptor Agonists: Buspar, Imitrex
- Dopamine Agonists: Amantadine, Wellbutrin, Levodopa
- Other Non-specific Serotonin increase: Lithium