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Congenital Zika Syndrome
Aka: Congenital Zika Syndrome
- See Also
- Zika Virus
- Epidemiology
- Identified in winter of 2015-16 in Brazil, with thousands of new Microcephaly cases
- Pathophysiology
- Perinatal or in utero transmission from mothers infected during pregnancy (esp. first and second trimester)
- Signs: Head
- Severe Microcephaly (1-13% risk with prenatal Zika infection)
- Misshapen skull
- Scalp rugae
- Intracranial calcifications
- Complications
- Eye
- Chorioretinal atrophy or scarring
- Neurologic
- Vision and Hearing Deficits
- Cognitive disorders
- Motor disorders, hypertonia, spasticity, Tremors
- Seizure Disorders
- Swallowing Disorders
- Orthopedic
- Clubfoot
- Arthrogryposis (joint contractures)
- Resources
- U.S. Zika Pregnancy Registry
- https://www.cdc.gov/zika/reporting/registry.html
- Zika Active Pregnancy Surveillance System (Puerto Rico)
- https://www.cdc.gov/zika/reporting/zapss.html
- References
- Huntington (2016) Am Fam Physician 94(7): 551-7 [PubMed]
- Igbinosa (2017) Am Fam Physician 95(8): 507-13 [PubMed]