Infectious Disease Book


Immunosuppressive Agent

Aka: Immunosuppressive Agent, Immunosuppressive Drug, Immunosupressant, Immunosuppression, Immune Suppression, Therapeutic Immunosuppression
  1. See Also
    1. Immunodeficiency
    2. Biological Agent
    3. Chemotherapy
    4. Corticosteroids
  2. Types
    1. Corticosteroids
    2. Chemotherapy
    3. Transplant Antirejection Drugs
    4. Autoimmune Condition Agents (e.g. Rheumatoid Arthritis Remittive Agents, Biological Agent)
  3. Mechanism
    1. Lymphocyte depletion
    2. Plasma exchange removal of Antibody
    3. Corticosteroids (Cytokine suppression)
    4. Interrupt Lymphocyte activity
    5. Block specific Antigen response
    6. Antigen Desensitization

Therapeutic immunosuppression (C0021079)

Definition (NCI_NCI-GLOSS) Therapy used to decrease the body's immune response, such as drugs given to prevent transplant rejection.
Definition (CSP) deliberate suppression of immune system function for experimental or therapeutic purposes.
Definition (MSH) Deliberate prevention or diminution of the host's immune response. It may be nonspecific as in the administration of immunosuppressive agents (drugs or radiation) or by lymphocyte depletion or may be specific as in desensitization or the simultaneous administration of antigen and immunosuppressive drugs.
Concepts Therapeutic or Preventive Procedure (T061)
MSH D007165
SnomedCT 86553008
English Anti Rejection Therapy, Anti-Rejection Therapies, Anti-Rejection Therapy, Antirejection Therapies, Antirejection Therapy, Immunosuppression, Immunosuppressions, Therapy, Anti-Rejection, Therapy, Antirejection, artificial immunosuppression, immunosuppression, THER ANTI REJECTION, THER ANTIREJECTION, ANTI REJECTION THER, ANTIREJECTION THER, therapeutic immunosuppression, Therapeutic immunosuppression, immune suppression, anti-rejection therapy, immunosuppressive therapies, immunosuppressive therapy, Immunosuppressive therapy (procedure), Immunosuppressive therapy, Immunosuppressive therapy, NOS, Immunosuppressive Therapy
Swedish Immunsuppression
Czech imunosuprese
Finnish Immunosuppressio
Japanese 免疫抑制(治療), 免疫抑制療法, 抗拒絶反応療法, 免疫学的抑制, 抗拒絶療法
French Thérapie anti-rejet, Immunodépression thérapeutique, Immunosuppression thérapeutique, Thérapie antirejet, Immuno-suppression thérapeutique
Italian Terapia antirigetto, Terapia anti-rigetto, Immunosoppressione
Polish Immunosupresja
Norwegian Immunsuppresjon
Portuguese Terapia Antirrejeição, Imunossupressão
Spanish terapia inmunosupresora (procedimiento), terapia inmunosupresora, Terapia Anti-Rechazo, Inmunosupresión
German Immunsuppression, Abstoßungsbehandlung, Therapie der Abstoßungsreaktion
Dutch Antirejectietherapie, Immunosuppressie
Derived from the NIH UMLS (Unified Medical Language System)

Immunosuppressive Agents (C0021081)

Definition (NCI_NCI-GLOSS) An agent that decreases the body's immune responses. It reduces the body's ability to fight infections and other diseases, such as cancer. Immunosuppressants may be used to keep a person from rejecting a bone marrow or organ transplant. They are also used in the treatment of conditions marked by over-active immune responses, such as auto-immune diseases and allergies.
Definition (CSP) agents that suppress immune function by one of several mechanisms of action; cytotoxic immunosuppressants act by inhibiting DNA synthesis; others may act through activation of suppressor T-cell populations or by inhibiting the activation of helper cells.
Definition (MSH) Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.
Concepts Pharmacologic Substance (T121) , Immunologic Factor (T129)
MSH D007166
SnomedCT 69431002, 372823004
LNC LP31454-9
English Agents, Immunosuppressive, Immunosuppressive Agents, Immunosuppressants, IMMUNE SUPPRESSANTS, Immunosupressant agent, NOS, immunosuppressive (medication), immunosuppressive, [IM600] IMMUNE SUPPRESSANTS, Immunosuppressives, immune suppressants, immune suppressant, immunosuppressants, immunosuppressives, immunosuppressant, immunosuppressive agents, IMMUNOSUPPRESSANTS, Immunosuppressive agents, Immunosuppressant, Immunosuppressant (product), Immunosuppressant (substance), Immunosuppressive agent, Immunosuppressant agent, NOS, Immunosuppressive agent, NOS, Immune Suppressants
French Agents immunodépresseurs, Médicaments immunodépresseurs, Immuno-suppresseurs, Immunodépresseurs, Médicaments immunosuppresseurs, Immunosuppresseurs, Immuno-dépresseurs, Agents immunosuppresseurs, Médicaments immuno-suppresseurs, Médicaments immuno-dépresseurs
Swedish Immunhämmande medel
Czech imunosupresiva
Finnish Immunosuppressiiviset lääkkeet
Italian Immunosoppressori, Immunodepressivi
Polish Leki immunosupresyjne
Japanese 免疫抑制作用剤, 免疫抑制剤, 免疫抑制物質, 免疫抑制薬
Spanish Inmunosupresores, Agentes Inmunosupresores, Fármacos Inmunosupresores, agente inmunosupresor, droga inmunosupresora, inmunosupresor (producto), inmunosupresor (sustancia), inmunosupresor
Portuguese Fármacos Imunossupressores, Agentes Imunossupressores, Imunossupressores
German Immunsuppressiva
Derived from the NIH UMLS (Unified Medical Language System)

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