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Genital Herpes in Pregnancy
Aka: Genital Herpes in Pregnancy
- See Also
- Neonatal Herpes Simplex Virus
- Genital Herpes
- Primary Genital Herpes
- Secondary Genital Herpes
- Findings
- See Genital Herpes
- See Primary Genital Herpes
- See Secondary Genital Herpes
- Management: Pregnancy (> 36 weeks gestation)
- Treat primary HSV II infections on Primary Genital Herpes protocol
- Culture Cervix and lesion every 3-5 days until negative
- Acyclovir if indicated
- See below for prevention of Neonatal HSV transmission
- Cesarean Section indications
- HSV II Culture positive
- All women with active HSV II lesions
- Complications: Vertical transmission
- Neonatal Herpes Simplex Virus
- Prevention: Neonatal Herpes Simplex Virus transmission
- Prevent transmission from HSV positive partner
- Abstinence or Condom use during pregnancy
- Consider Vaccine below
- Antiviral prophylaxis for HSV positive partner
- Avoid oral-genital contact if Oral HSV in partner
- Vaccinations as of yet are experimental (e.g. HSV-2 Glycoprotein-D-Adjuvant Vaccine)
- Stanberry (2002) N Engl J Med 347:1652-61 [PubMed]
- Identify HSV II risks in all pregnant women
- Personal history of HSV II
- Partners with HSV II
- Screen at first Prenatal Visit and perinatally
- Cesarean Section for all women with active lesions
- Acyclovir
- Acyclovir 400 mg orally twice daily from 36 weeks until delivery
- Indicated in all pregnant women with Genital Herpes history
- Also treat any Primary Genital Herpes outbreak during pregnancy
- Also treat all women with near-term or perinatal Genital Herpes outbreak
- References
- Sheffield (2003) Obstet Gynecol 102:1396-403 [PubMed]
- References
- Beauman (2005) Am Fam Physician 72(8):1527-34 [PubMed]
- Groves (2016) Am Fam Physician 93(11): 928-34 [PubMed]
- Nadelman (2000) Postgrad Med 107(3):189-95 [PubMed]