Infectious Disease Book

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Gonorrhea Antigen

Aka: Gonorrhea Antigen, Gonococcal Antigen, Gonozyme
  1. Indications
    1. Testing for NeisseriaGonorrhea: Urethra, Cervix
    2. Not indicated for GC testing of throat or anus
  2. Mechanism
    1. Enzyme Immunoassay
  3. Technique
    1. Cervical Specimen
      1. Avoid lubricating gel (may kill Gonococcus)
      2. Wipe clean Cervix with swab
      3. Compress Cervix between speculum blades
        1. Produces endocervical exudate
      4. Rotate swab in endocervical canal for 10-30 seconds
      5. Avoid touching side walls of vagina with swab
    2. Urethra Specimen (Males)
      1. Gently scrape anterior meatus with swab
  4. Efficacy
    1. Sensitivity: 98% Men, 88% Women
    2. Specificity: 100% Men, 98% Women
  5. References
    1. Bakerman (1984) ABCs of Interpretive Lab Data

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